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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13
All Species:
27.27
Human Site:
S1170
Identified Species:
50
UniProt:
Q9UHV7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHV7
NP_005112.2
2174
239318
S1170
F
E
A
L
R
A
T
S
A
E
H
V
N
G
G
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
S1184
F
E
A
L
R
A
T
S
A
E
H
V
N
G
G
Rhesus Macaque
Macaca mulatta
XP_001110128
2174
239364
S1170
F
E
A
L
R
G
T
S
A
E
H
V
N
G
G
Dog
Lupus familis
XP_537704
2182
240593
S1178
F
E
A
L
R
A
T
S
A
E
H
V
N
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWW4
2171
238573
S1169
F
E
A
L
R
A
S
S
V
E
N
V
N
G
G
Rat
Rattus norvegicus
NP_001100505
2040
223488
C1064
I
L
L
L
Q
D
Q
C
T
N
L
F
S
P
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
S1167
F
D
A
L
R
A
T
S
A
E
H
V
S
G
G
Chicken
Gallus gallus
XP_415884
2225
244861
S1221
F
E
A
L
R
A
T
S
V
E
H
G
S
A
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
Y1114
S
A
V
M
N
R
R
Y
G
N
G
A
G
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
S1612
T
L
L
S
I
I
Q
S
L
S
R
K
N
Q
N
Honey Bee
Apis mellifera
XP_393643
1982
216109
Y1006
A
H
Q
A
G
L
F
Y
E
D
E
M
E
I
T
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
Q1671
H
D
L
A
L
L
D
Q
I
R
Q
M
A
F
S
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
M151
T
F
H
K
D
N
P
M
L
A
G
M
P
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
97.7
94.1
N.A.
92.5
87.8
N.A.
89.5
84.6
N.A.
64.8
N.A.
24.7
35
21
25.7
Protein Similarity:
100
98.3
98.4
96
N.A.
96.4
91.2
N.A.
94
90.5
N.A.
76.9
N.A.
41.3
51.5
37.4
36
P-Site Identity:
100
100
93.3
100
N.A.
80
6.6
N.A.
86.6
73.3
N.A.
0
N.A.
13.3
0
0
0
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
20
N.A.
100
80
N.A.
6.6
N.A.
13.3
13.3
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
54
16
0
47
0
0
39
8
0
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
8
8
8
0
0
8
0
0
0
8
0
% D
% Glu:
0
47
0
0
0
0
0
0
8
54
8
0
8
0
0
% E
% Phe:
54
8
0
0
0
0
8
0
0
0
0
8
0
8
16
% F
% Gly:
0
0
0
0
8
8
0
0
8
0
16
8
8
47
54
% G
% His:
8
8
8
0
0
0
0
0
0
0
47
0
0
0
0
% H
% Ile:
8
0
0
0
8
8
0
0
8
0
0
0
0
8
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
16
24
62
8
16
0
0
16
0
8
0
0
8
0
% L
% Met:
0
0
0
8
0
0
0
8
0
0
0
24
0
0
0
% M
% Asn:
0
0
0
0
8
8
0
0
0
16
8
0
47
0
8
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
8
8
0
% P
% Gln:
0
0
8
0
8
0
16
8
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
0
54
8
8
0
0
8
8
0
0
0
8
% R
% Ser:
8
0
0
8
0
0
8
62
0
8
0
0
24
0
8
% S
% Thr:
16
0
0
0
0
0
47
0
8
0
0
0
0
0
8
% T
% Val:
0
0
8
0
0
0
0
0
16
0
0
47
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _